HYDRATION: A NEW PARADIGM
Written by: Paul Harris
A common denominator in all living things is the need for water. Building the molecules of life is only possible when their components are dissolved in water. Adequate water intake, and utilization is indispensable to all microorganisms, plants, and animals. The human body is composed of 25 per cent solid matter, and 75 per cent water.
Water is essential to life, and is a key to the rate of aging, immunity, and all biochemical processes that occur in biological systems, especially the brain which consist of about 85 percent water. Water makes life possible because it has unique physical, and chemical properties.
Most people are unaware of what happens to the body if it is not adequately hydrated. Whole metabolic systems are disturbed, often severely by dehydration.
Some signs of dehydration are, bloating or abdominal discomfort that occur after drinking water, dry mouth, or difficulty forming saliva , disinclination to drink water because of the taste... sometimes not drinking water, but obtaining water from coffee, tea, fruit drinks, or manufactured beverages. Other symptoms include insatiable thirst... craving and eating sweets followed by drinking a lot of fluids; lack of elasticity in skin and water retention. Unfortunately, many of these beverages accelerate water loss rather than increasing hydration.
Dr. Batmanghelidj, a medical researcher, presents a new paradigm regarding the function and role of water in human biochemistry. Scientists have assumed that the solute composition is the governing factor of all biological functions of the body. Water is considered as only a solvent...a space filler, and means of material transport in the body. Science considers the human body as a huge "test tube" with a myriad of solids, and the water in the body as chemically irrelevant "packing material."
It is my belief, and the belief of Dr. Batmanghelidj, that the water (solvent content) of the body indeed governs the activity of all the solutes, and directs all functions of the body. When the water metabolism of the body becomes disturbed, various symptoms or signals appear. This indicates a "system" disturbance associated with water regulation. In consideration of this view, the importance of water intake has indeed been established. If there is an excessive production or over activity of the regulating neurotransmitter systems (histamine and its subordinate agents), one could assume that initially they are becoming involved in the regulatory action of water management (rationing) of the body. It is erroneous to block their action by pharmaceutical intervention; their purpose should be satisfied by achieving optimum levels of hydration.
Water regulates all functions of the body, including the activity of all the solutes that are dissolved in it. The bonds that hold hydrogen and oxygen atoms together, permit water to be fluid at the environmental temperatures compatible with life. Water forms the aqueous medium that delivers nutrients to the cells. Water also dissolves and dilutes poisonous wastes, and removes them from the cells. Long-term health maintenance can only be achieved through efficient hydration.
THE THREE STAGES OF WATER REGULATION
According to Dr. Batmanghelidj, water regulation is divided into three different stages during ones lifetime. The first stage is the life is the life of a fetus in the uterus of the mother. The second stage occurs approximately between the ages of 18 to 25 - when full height is attained. The third stage is from adulthood to the death of the person. Dr. Batmanghelidj points out that dehydration begins at an early age, and becomes chronic due to a gradually failing thirst sensation. With aging, the intracellular water content diminishes to the point that the ratio of the volume of water inside the cell, compared to extra-cellular water, changes from a figure of 1.1 to almost 0.8. This is a significant change. Since our daily consumption of water directly contributes to cellular function, the decrease in our intake affect the quality of cellular activity. The end result is chronic dehydration, which contributes to disease symptoms. In many cases these symptoms are the direct result of a water shortage in the body. Frequently, these symptoms are treated with medications, ignoring the body's cry for water.
THE MULTIPLE ROLE OF WATER
Water plays other important roles in the body than just being a unique solvent, and means of transport. Hydrolysis, or hydroelectric energy (voltage gradient) is generated at the cell membrane, and is stored in the form of A TP. This is used for elemental (cation) exchanges, particularly in neurotransmission. Another important function of water is that of forming a specific structure pattern that is utilized as the adhesive material in the bondage of the cellular architecture.
The brain cells manufacture products that are delivered to their target in the nerve endings for use in the communication of messages on "waterways." According to Dr. Batmanghelidj, there appears to be micro streams along the length of nerves that "float" the packaged materials along "guidelines," called microtubules. Enzymes and proteins are more functional in an optimally hydrated environment - this is true of all cell membrane receptors... On the contrary, enzymes and proteins operate with less efficiency in a dehydrated state.
It is becoming more obvious that subclinical, and clinical dehydration activates the histamine directed neurotransmitter system, which promotes water intake, and management. With this system intact, water that is in circulation can be recirculated, or can be drawn away from other areas. In addition, prostaglandin's, kinins, renin-angiotensin, and vasopressin are subordinate systems employed as the intermediary agents. It is important to remember that there are no water reservoirs the body can pull from, rather it operates a priority distribution system commensurate to water intake, and uptake.
It is interesting to note that in amphibian species, histamine production becomes pronounced when the animal is dehydrated. However, under normal circumstances, production is minimal. Dr. Batmanghelidj states, "For rationing regulation of the available water in dehydrated animals, drought management - the naturally coupled response is a proportionate increase in the production rate, and storage of the neurotransmitter - histamine. When they come across pain-sensing nerves in the body, histamine, and it's subordinate water intake, and distribution regulator's, prostaglandin's, kinins, and PAF (another associated agent,) also cause
pain." Based upon this new shift in thinking, many times, chronic pain caused by excessive histamine production could indeed be the direct result of a water shortage in the body, and should be treated as such.
Dyspeptic pain is indicative of dehydration, and is a thirst signal. More specifically - gastritis pain, duodenitis, and heartburn are important signals of dehydration. However, ulcers require more rigid dietary management in addition to water intake. Dr. Batmanghe1idj published an editorial article in the Journal of Clinical Gastroenterology in 1983, in which he describes his
successful treatment of over 3000 persons with dyspeptic pain. His only medication was water. He states, "They all responded to an increase in their water intake, and their clinical problems associated with the pain disappeared"
Research has shown that after consumption of a glass of water - it is immediately transported to the intestine and absorbed. Within 30 minutes, almost the same quantity of water is secreted in the mucosal glandular layer of the stomach ready to assist in the digestive process. Adequate amounts of water are critical for good digestion. The glandular layer of the stomach is normally covered in mucus. Mucus consists of 98 per cent water, and two per cent, the physical "scaffolding" that traps water. This protects the inner lining of the stomach by acting as a natural buffer state.
An important part of this buffer system is sodium bicarbonate. Sodium bicarb becomes trapped in the water layer. This provides protection for the stomach from excessive acid production, by neutralizing it. The result of this natural biochemical reaction is an increased salt production, (sodium from the bicarb, and chlorine from the acid). Excess sodium changes the water holding properties of the "scaffolding" material of mucus. Excessive acid neutralization, and deposition of sodium in the mucus layer would make it less homogeneous, and will allow penetration to the mucosal layer; resulting in dyspeptic pain. The resecretion of water through the mucus layer appears to exert a "back-washing effect" on the mucus layer, removing the salt deposits. The effectiveness of this phenomenon of course is dependent upon water intake.
As a note of caution: Pains that do not respond to an increased water intake over a period of time, could be the result of a serious pathological condition. It would be prudent for you to consult your family physician.
Other conditions responding well to proper hydration are: Colitis, and false appendicitis pain. Rheumatoid arthritis pains can initially be considered indicators of a lack of adequate hydration in the affected join cartilage surfaces. The cartilage surfaces of bones in a joint contain much water. This "held water" provides a lubricating quality. A well hydrated joint obtains its nutrition from the blood supply to its. base attachment to the bone. A dehydrated joint will get some form of fluid circulation from the capsule of the joint, producing swelling, and tenderness in the joint capsule.
LOW BACK PAIN
Dehydration can effect any or all parts of the body - especially the spine, intervertebral joints, and their disk structure. Hydraulic properties of water stored in the disk core as well as other parts of the musculoskeletal system, are indeed dependent upon adequate hydration. Contact surfaces in the spinal vertebrae require waterfor its lubricating property. The disc core within the intervertebral space also contains water - and support the compression weight of the upper body. Dr. Batmanghelidj states, "Fully 75 per cent of the weight of the upper body is supported by the water volume that is stored in the disc core 25 per cent is supported by the fibrous materials around the disc". The 5th lumbar is affected in the majority of cases. Water appears to be a universal lubricating agent for all joints through an intermittent vacuum effect.
The water is then dispersed by pressure brought about by joint movement. Factors involved in relieving back pain are:
* Increased water intake
* Specific exercises (enhances uptake of water into the disc space through a vacuum effect .
*Regular chiropractic adjustment
Neck pain is also exacerbated by dehydration, and poor posture. Adequate hydration, and exercise will help establish adequate circulation, and a vacuum within the disc spaces.
COMPENSATION MECHANISMS ASSOCIATED WITH DEHYDRATION
Dehydration triggers a series of biochemical events that are the same as the body's response to stress. Dehydration produces stress, and subsequently actuates several strong hormones which "mop" up some of the water reserves of the body. This in turn will elicit further dehydration.
The body's reaction to stress is to "fight or flight" response, which in turn causes secretion of hormones. Initially, ACTH levels are increased with a consequent increase in cortisol secretion. Endorphins, cortisone, prolactin, vasopressin, and rennin-angiotensin are also part of
the hormonal crisis management team. Endorphin secretion is induced by stress, and prepares the body for impending danger or hardship. Endorphins also increases the body's pain threshold.
Cortisone: Hydrocortisone, 17-hydroxy corticosteroid, 17 -OHCS is a hormone secreted by the adrenal cortex. The raw material for cortisol is cholesterol. Exogenous cholesterol in normal conditions accounts for 80 per cent of the total cortisol production, and 25 per cent being synthesized by the adrenal cortex. Cortisone mobilizes the body's store of raw materials, such as fat, and protein for energy conversion - and synthesis of extra neurotransmitters.
Prolactin: Prolactin is similar to growth hormone due to its specific action on tissues. It also has no regulatory effect on a secondary endocrine gland. The only established function of prolactin in man is the initiation, and maintenance of lactation. .. even if there is dehydration. Although the nutritional components of milk are indeed important, the water content is of primary importance to the developing fetus. During mitosis a single cell gives rise to a daughter cell, and 75 per cent or more of its volume requires water. Hydration of the daughter cell enables it to access its other dissolved contents.
Dr. Batmanghelidj alludes to a study conducted on mice that revealed when prolactin was increased, there was an increase in mammary tumors. He believes that due to the similarity of prolactin to growth hormone - there is more than a casual relationship to chronic dehydration, persistent prolactin secretion, and tumor production in the breast.
Vasopressin: Vasopressin has a regulatory action on the bioavailability of water in some cells of the body. It also has a vasoconstrictive effect on the capillaries it activates. The architecture of the cell membrane is bilayer. The adhesive property of water is partially responsible for cell wall integrity. According to Dr. Batmanghelidj, enzymes travel, and perform their varied functions in a connecting passageway located between the bilayers of the cell membrane.
He characterizes this waterway as a "water filled beltway". The body has a unique safeguard against significant water loss in the beltway. Dr.Batmanghelidj states, "The vasopressin receptor converts to a 'showerhead' structure when vasopressin hormone reaches the cell membrane, and fuses with its specially designed receptor". Vasopressin plays a key role in water management, and rationing in dehydration.
Rennin-Angiotensin system: This system is a primary regulator of aldosterone, which is produced by the zone glomerulosa. The juxtaglomerular apparatus of the nephron is responsible for the release of rennin (an enzyme) into the general circulation. Rennin-angiotensin (RA) plays a crucial role in water regulation, and is a subordinate mechanism to histamine activation in the brain.
The (RA) system is extremely sensitive to decreased levels of fluid volume in the body, and sodium depletion. The (RA) system is also responsible for vasoconstrictive action on the capillary bed, and the vascular system. This system is largely responsible for restoration of fluid volume in the body. Adequate hydration is essential since hypertension can occur from prolonged (RA) activity
THE SLEEPER PHENOMENON
The answer to rehydration is not always solved by increasing water intake. Though dehydrated, the body may not be able to utilize more water. Glenn Braddy, an Australian architect, and nutrition researcher, has devoted much time to alchemical solutions to human biological puzzles, such as dehydration. Mr. Braddy, and IFA (International Foundation of Alchemists) have discovered the "Sleeper Phenomenon". In simple terms, a 'sleeper' is a vital component of body chemistry which has gone into a state of suspended activity, a 'hibernation'. In other words, the component is indeed present in the body, but not functionally active.
According to Braddy, the sleeper can be an amino acid, vitamin, or mineral. As long as the sleeper remains inactive, it will promote symptoms in the patient. If a patient had a magnesium sleeper, the mineral would be present in the body, but inactive or dormant. The symptomatic result would be that of a magnesium deficiency. The normal approach to a mineral deficiency is to supply that mineral through a dietary supplement. However, if magnesium is the sleeper the problem will not be solved by adding magnesium. The obvious answer is to activate the sleeper. The cause according to Braddy, is almost invariably dehydration. It is crucial to point out that in many cases, increasing water intake does not equal uptake or utilization. Many people often identify symptoms of dehydration, and increase their water intake but fail to rehydrate. This could possibly explain why some individuals take certain nutrients, and show little benefit.
The best approach to solving this problem appears to be rehydration, and finding an efficient way of getting water into the body. The key to achieving this is to provide a transporter that will facilitate the uptake of water into the body.
Symptoms of insufficient uptake of water include, remaining thirsty after drinking... disliking the taste of water, or bloating after drinking water. There are many transporters that can be used. Sub-acid fruit juices appear to have the best hydrating effect.
One such transporter that may come as a surprise is caffeine. Caffeine is an effective transporter, especially for women. Another transporter is Dandelion, which is particularly important for men. Braddy states, "What is important to identify here is that many people who crave sugar, coffee, and other caffeine sources, such as Coca-Cola, and chocolate, are actually using those foods, and beverages to promote rehydration - and address sleeper problems in the process - although temporarily n. In other words, the body is aware of the sleeper, and actually promotes the craving, or drive to particular elements which can activate the sleeper.
An important point to remember, is that cravings are not the cause of the problem, but the result of the problem. Unfortunately; the intake of these foods can only temporarily alleviate the sleeper problem. The fact that the person craves other beverages, and certain foods - and not water, is a strong indicator of the inability to absorb water.
The notion of increasing caffeine intake through coffee, and tea to enhance uptake of water is not a viable option according to Mr. Braddy. A simple alternative is to add Synergy's "Hydration Plus." formula to your choice of sub-acid fruit juice, and water.
Organic Coffee, Germanium, Silica, and Dandelion
Germanium, and Silica: conduct electrons, or amplifies energy - and can also store electricity to a point, and then allows current flow. The transfer of electrons is highly dependent on the availability of molecular oxygen. In terms of how this influences biological systems - it enhances intracellular communication as well as increasing assimilation, and utilization of elements at the cellular level.
INSTRUCTION FOR USE
Use flat (non-carbonated) mineral water, or reverse osmosis water mixed with one of the following sub-acid fruit juices: Apple juice, pear juice, ripe pineapple juice, watermelon juice, or fresh lemonade.
The ratio of water to juice should be a minimum of 3 to 1- three parts water- to one part juice. You can add a little more than 1/3 juice to sweeten the mixture if you wish.
To an 8 oz. Mixture (juice & water) add ten drops of Hydration Plus, or add 30 drops to a quart of the mixture.
Consume four to eight- eight ounce glasses of this mixture throughout the day, between meals. If you are experiencing digestive problems, it is important to consume one of these glasses, thirty minutes before each meal.
NOTE: If you have kidney disease, begin with one glass of hydration mix per day, and slowly increase up to the desired amount. This will allow the kidneys to adjust to the increased fluid uptake, and utilization.
Drink the herbal hydration fluid - Monday through Saturday... consume only water on Sunday, then repeat the same procedure at the beginning of each week.
Composition Sarsaparilla MT, Coffea Cruda MT, Juniper MT, Wild Yam MT, Dandelion MT, Germanium 1-3-12X, Ubiquinone 2-3-6-30X, Silica 3-9-12X Indications: For temporary relief of dry mouth, dyspepsia. Enhances uptake, and utilization of water.. Improves cellular communication.